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Posted On Jan 07, 2017

 
The latest installment of the Oman Medical Journal was issued this January. Oman Med J’s Volume 32, Issue 1, January 2017 contains an editorial, review article, eight original articles, four case reports, clinical quiz and clinical notes. In this issue, the journal approaches important issues in medical care and scientific research in medicine, and contributes new knowledge to experts and scholars as well as the public.
The editorial titled "Immunotherapy in Cancer: Incremental Gain or a Quantum Leap?" talks about improvement in survival of patients with cancer. The editorial gives some information about using of immune checkpoint inhibitors for the management of various cancers. Difficult-to-treat cancers respond to the treatment, and patients live longer with good quality of life. Given the excitement, the all-important question to ask is whether ‘immunotherapy’ will prove to be another incremental gain, frequently observed in cancer practice over the past half-century, or is it going to be one of the few quantum leaps, rarely observed in clinical practice?. Therefore, due to efficacy, and favorable risk-benefit profile, immune checkpoint inhibitors are being regarded as a game-changer in several cancers. Although immune checkpoint inhibitors demonstrate efficacy across multiple tumor types, it is also clear that a subgroup of patients do not respond. Also, toxicity may occur, especially in the form of less-described ‘financial toxicity’. What remains to be seen is whether this form of treatment would produce another small incremental gain, or would prove to be a quantum leap in the war against cancer.
 
The review article titled "Tobacco control in Oman: It’s time to get serious!" talks about Oman’s experience in tobacco control by providing a descriptive analysis of the evolution of tobacco control policies in relation to the country’s international obligations. The review concludes that Oman needs to accelerate action in adopting the highest attainable policies recommended by the World Health Organization’s MPOWER package.
One of the original articles titled "Incidence and Etiology of Surgical Site Infections in Appendectomies: A 3-Year Prospective Study" aims to describe the incidence of SSIs in appendectomies performed during a three-year period (January 2013 to December 2015) in a community hospital in Qatar, and compare this with external benchmarks. The study concluded that the incidence of SSI in appendectomy, which could be used as a benchmark for the facility improvement program. The high frequency of multidrug-resistant organisms in SSI requires additional studies focused on evaluating the effectiveness of the current preventive practices with a particular reference to antimicrobial prophylaxis.
 
Another original article titled "In-Hospital and One-Year Clinical Outcome of Percutaneous Coronary Intervention in a Tertiary Hospital in Oman: Oman PCI Registry" aims to investigate the in-hospital and one-year clinical outcome of patients treated with percutaneous coronary intervention (PCI) in a tertiary hospital in Oman. The study concluded that Omani patients treated with PCI were much younger than Western patients with a high prevalence of risk factors. Successful PCI was achieved in a large percentage of patients with a low incidence of in-hospital complications and mortality. At one-year follow-up, the majority patients had a good clinical outcome.
 
 
The following case reports titles are also included in this issue: A Novel Deletion Mutation of Exon 2 of the C19orf12 Gene in an Omani Family with Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN), Imported Case of Melioidosis in Oman: Case Report, Hamartoma of Palatine Tonsil: A Rare Case Nodular Fasciitis of the Neck Causing Emergency: A Case Report, and Pancreatic Tuberculosis with Markedly Elevated CA 19-9 Levels: A Diagnostic Pitfall An Unusual Cause of Post Abortal Fever Requiring Prompt Surgical Intervention: A Pyomyoma and its Imaging Features.
 
Oman Medical Journal was founded in 1984. It is a peer-reviewed journal, publishes six issues a year by Oman Medical Specialty Board. It intends to engage and inform doctors, researchers and other health professionals by publishing a wide range of peer-reviewed articles in various medical disciplines.  If you want to see the old issues you can visit our website http://www.omjournal.org.